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Determination of the Level of Toxic Heavy Metals in Selected Traditional Medicinal Plants in Sheka Zone, Southwest Ethiopia

Received: 17 August 2022    Accepted: 13 September 2022    Published: 28 September 2022
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Abstract

Although medicinal plants may be produced in polluted soil or water settings, their extracts have long been utilized to treat illnesses affecting the general populace. Many of these herbs are collected and prepared in an unsanitary way by untrained local natural healers and other sellers. As a result, there is a chance that potentially harmful elements from the environment will contaminate the area. In this study, the five most prevalent poisonous heavy metals (arsenic, cadmium, chromium, lead, and mercury) were measured in five medicinal plants used extensively in southwest Ethiopia's Sheka Zone., including Bersama abyssinica, Calpurnia aurea, Croton macrostachyus, Eucalyptus globules, and Solanum incanum. The Tepi district in southwest Ethiopia provided the plant samples, which were then cleaned, dried, disinfected with 0.1% HgCl, digested with 69% HNO3 and 35% H2O2, and then subjected to AAS analysis. According to the study's findings, neither cadmium nor mercury was found in Solanum incanum. Additionally, Bersama abyssinica and Croton macrostachyus also do not contain mercury. Cd (below detection limit (BDL) to 0.6012 ppm), As (below detection limit (BDL) to 0.032 ppm), Hg (below detection limit (BDL) to 0.020 ppm), Cr (0.75 0.18 to 1.32 0.21), and Pb (below detection limit (BDL) to 0.0200 ppm) were the harmful heavy metals with the widest concentration ranges (0.01013 ppm to 0.4012 ppm). The findings demonstrate that while these plant species were below the WHO permitted limits for consumed therapeutic herbs; their usage for disease prevention will not cause heavy metal toxicity and may even be advantageous to users who are deficient in micronutrients.

Published in Modern Chemistry (Volume 10, Issue 3)
DOI 10.11648/j.mc.20221003.14
Page(s) 93-97
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Spectrophotometer, Heavy Metals, Medicinal Plants

References
[1] Wachtel-Galor, S., Yuen, J., Buswell, J. A., & Benzie, I. F. (2011). Ganoderma lucidum (Lingzhi or Reishi). Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition.
[2] Jaradat, N. A. (2005). Medical plants utilized in Palestinian folk medicine for treatment of diabetes mellitus and cardiac diseases. Al-Aqsa University Journal (Natural Sciences Series), 9 (1), 1-28.
[3] Holliday, I. (2003). Traditional medicines in modern societies: an exploration of integrationist options through East Asian experience. The Journal of medicine and philosophy, 28 (3), 373-389.
[4] Hussain, I., Khattak, M. R., Khan, F. A., Rehman, I., & Khan, F. U. (2011). Analysis of heavy metals in selected medicinal plants from Dir, Swat and Peshawar Districts of Khyber Pakhtunkhwa. Journal of the Chemical Society of Pakistan, 33 (4), 495-498.
[5] World Health Organization. (2007). Assessment of the risk of hepatotoxicity with kava products. WHO Regional Office Europe.
[6] Abera, B. (2014). Medicinal plants used in traditional medicine by Oromo people, Ghimbi District, Southwest Ethiopia. Journal of ethnobiology and ethnomedicine, 10 (1), 1-15.
[7] Abebe, W. (2016). An overview of Ethiopian traditional medicinal plants used for cancer treatment. European Journal of Medicinal Plants, 14 (4).
[8] Jima, T. T., & Megersa, M. (2018). Ethnobotanical study of medicinal plants used to treat human diseases in Berbere District, Bale Zone of Oromia Regional State, South East Ethiopia. Evidence-Based Complementary and Alternative Medicine, 2018.
[9] Lulekal, E., Kelbessa, E., Bekele, T., & Yineger, H. (2008). An ethnobotanical study of medicinal plants in Mana Angetu District, southeastern Ethiopia. Journal of ethnobiology and Ethnomedicine, 4 (1), 1-10.
[10] Birhanu, Z. (2013). Traditional use of medicinal plants by the ethnic groups of Gondar Zuria District, North-Western Ethiopia. Journal of Natural Remedies, 13 (1), 46-53.
[11] Teklehaymanot, T. (2009). Ethnobotanical study of knowledge and medicinal plants use by the people in Dek Island in Ethiopia. Journal of Ethnopharmacology, 124 (1), 69-78.
[12] Belay, K. (2015). Acid digestion of spice samples for heavy metal analysis using wet digestion heating by atomic absorption spectroscopy. International Journal of Informative & Futuristic Research, 1 (11), 1-8.
[13] Osman, N. A., Ujang, F. A., Roslan, A. M., Ibrahim, M. F., & Hassan, M. A. (2020). The effect of palm oil mill effluent final discharge on the characteristics of Pennisetum purpureum. Scientific reports, 10 (1), 1-10.
[14] World Health Organization. (2007). Quality assurance of pharmaceuticals: a compendium of guidelines and related materials. Good manufacturing practices and inspection (Vol. 2). World Health Organization.
[15] Martin, S., & Griswold, W. (2009). Human health effects of heavy metals. Environmental Science and Technology briefs for citizens, 15, 1-6.
[16] Oteef, M. D., Fawy, K. F., Abd-Rabboh, H. S., & Idris, A. M. (2015). Levels of zinc, copper, cadmium, and lead in fruits and vegetables grown and consumed in Aseer Region, Saudi Arabia. Environmental monitoring and assessment, 187 (11), 1-11.
[17] Wuana, R. A., & Okieimen, F. E. (2011). Heavy metals in contaminated soils: a review of sources, chemistry, risks and best available strategies for remediation. International Scholarly Research Notices, 2011.
[18] Shazia, J., Muhammad, T. S., Sardar, K., & Muhammad, Q. H. (2010). Determination of major and trace elements in ten important folk therapeutic plants of Haripur basin, Pakistan. Journal of Medicinal Plants Research, 4 (7), 559-566.
[19] Khan, M. A., Ahmad, I., & Rahman, I. U. (2007). Effect of environmental pollution on heavy metals content of Withania somnifera. Journal of the Chinese Chemical Society, 54 (2), 339-343.
[20] Hayes, R. B. (1997). The carcinogenicity of metals in humans. Cancer Causes & Control, 8 (3), 371-385.
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    Dawit Darcha, Abebe Desalegne, Biruk Bezabeh Yimam, Turunesh Debela Jufar. (2022). Determination of the Level of Toxic Heavy Metals in Selected Traditional Medicinal Plants in Sheka Zone, Southwest Ethiopia. Modern Chemistry, 10(3), 93-97. https://doi.org/10.11648/j.mc.20221003.14

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    ACS Style

    Dawit Darcha; Abebe Desalegne; Biruk Bezabeh Yimam; Turunesh Debela Jufar. Determination of the Level of Toxic Heavy Metals in Selected Traditional Medicinal Plants in Sheka Zone, Southwest Ethiopia. Mod. Chem. 2022, 10(3), 93-97. doi: 10.11648/j.mc.20221003.14

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    AMA Style

    Dawit Darcha, Abebe Desalegne, Biruk Bezabeh Yimam, Turunesh Debela Jufar. Determination of the Level of Toxic Heavy Metals in Selected Traditional Medicinal Plants in Sheka Zone, Southwest Ethiopia. Mod Chem. 2022;10(3):93-97. doi: 10.11648/j.mc.20221003.14

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  • @article{10.11648/j.mc.20221003.14,
      author = {Dawit Darcha and Abebe Desalegne and Biruk Bezabeh Yimam and Turunesh Debela Jufar},
      title = {Determination of the Level of Toxic Heavy Metals in Selected Traditional Medicinal Plants in Sheka Zone, Southwest Ethiopia},
      journal = {Modern Chemistry},
      volume = {10},
      number = {3},
      pages = {93-97},
      doi = {10.11648/j.mc.20221003.14},
      url = {https://doi.org/10.11648/j.mc.20221003.14},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.mc.20221003.14},
      abstract = {Although medicinal plants may be produced in polluted soil or water settings, their extracts have long been utilized to treat illnesses affecting the general populace. Many of these herbs are collected and prepared in an unsanitary way by untrained local natural healers and other sellers. As a result, there is a chance that potentially harmful elements from the environment will contaminate the area. In this study, the five most prevalent poisonous heavy metals (arsenic, cadmium, chromium, lead, and mercury) were measured in five medicinal plants used extensively in southwest Ethiopia's Sheka Zone., including Bersama abyssinica, Calpurnia aurea, Croton macrostachyus, Eucalyptus globules, and Solanum incanum. The Tepi district in southwest Ethiopia provided the plant samples, which were then cleaned, dried, disinfected with 0.1% HgCl, digested with 69% HNO3 and 35% H2O2, and then subjected to AAS analysis. According to the study's findings, neither cadmium nor mercury was found in Solanum incanum. Additionally, Bersama abyssinica and Croton macrostachyus also do not contain mercury. Cd (below detection limit (BDL) to 0.6012 ppm), As (below detection limit (BDL) to 0.032 ppm), Hg (below detection limit (BDL) to 0.020 ppm), Cr (0.75 0.18 to 1.32 0.21), and Pb (below detection limit (BDL) to 0.0200 ppm) were the harmful heavy metals with the widest concentration ranges (0.01013 ppm to 0.4012 ppm). The findings demonstrate that while these plant species were below the WHO permitted limits for consumed therapeutic herbs; their usage for disease prevention will not cause heavy metal toxicity and may even be advantageous to users who are deficient in micronutrients.},
     year = {2022}
    }
    

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  • TY  - JOUR
    T1  - Determination of the Level of Toxic Heavy Metals in Selected Traditional Medicinal Plants in Sheka Zone, Southwest Ethiopia
    AU  - Dawit Darcha
    AU  - Abebe Desalegne
    AU  - Biruk Bezabeh Yimam
    AU  - Turunesh Debela Jufar
    Y1  - 2022/09/28
    PY  - 2022
    N1  - https://doi.org/10.11648/j.mc.20221003.14
    DO  - 10.11648/j.mc.20221003.14
    T2  - Modern Chemistry
    JF  - Modern Chemistry
    JO  - Modern Chemistry
    SP  - 93
    EP  - 97
    PB  - Science Publishing Group
    SN  - 2329-180X
    UR  - https://doi.org/10.11648/j.mc.20221003.14
    AB  - Although medicinal plants may be produced in polluted soil or water settings, their extracts have long been utilized to treat illnesses affecting the general populace. Many of these herbs are collected and prepared in an unsanitary way by untrained local natural healers and other sellers. As a result, there is a chance that potentially harmful elements from the environment will contaminate the area. In this study, the five most prevalent poisonous heavy metals (arsenic, cadmium, chromium, lead, and mercury) were measured in five medicinal plants used extensively in southwest Ethiopia's Sheka Zone., including Bersama abyssinica, Calpurnia aurea, Croton macrostachyus, Eucalyptus globules, and Solanum incanum. The Tepi district in southwest Ethiopia provided the plant samples, which were then cleaned, dried, disinfected with 0.1% HgCl, digested with 69% HNO3 and 35% H2O2, and then subjected to AAS analysis. According to the study's findings, neither cadmium nor mercury was found in Solanum incanum. Additionally, Bersama abyssinica and Croton macrostachyus also do not contain mercury. Cd (below detection limit (BDL) to 0.6012 ppm), As (below detection limit (BDL) to 0.032 ppm), Hg (below detection limit (BDL) to 0.020 ppm), Cr (0.75 0.18 to 1.32 0.21), and Pb (below detection limit (BDL) to 0.0200 ppm) were the harmful heavy metals with the widest concentration ranges (0.01013 ppm to 0.4012 ppm). The findings demonstrate that while these plant species were below the WHO permitted limits for consumed therapeutic herbs; their usage for disease prevention will not cause heavy metal toxicity and may even be advantageous to users who are deficient in micronutrients.
    VL  - 10
    IS  - 3
    ER  - 

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Author Information
  • College of Natural and Computational Sciences, Mizan Tepi University, Tepi, Ethiopia

  • College of Natural and Computational Sciences, Mizan Tepi University, Tepi, Ethiopia

  • College of Natural and Computational Sciences, Mizan Tepi University, Tepi, Ethiopia

  • College of Natural and Computational Sciences, Mizan Tepi University, Tepi, Ethiopia

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