Modern Chemistry

Volume 2, Issue 4, August 2014

  • An Improved Synthesis of Arenedicarboximides by Phosphine-Assisted Annulation of Arene-1,2-Dicarbaldehyde with N-Substituted Maleimide

    Mitsunori Oda, Haruki Shimosasa, Yoshimitsu Kumai, Akira Ohta, Ryuta Miyatake

    Issue: Volume 2, Issue 4, August 2014
    Pages: 29-35
    Received: 30 October 2014
    Accepted: 15 November 2014
    Published: 18 November 2014
    Abstract: Various arene-1,2-dicarbaldehydes react with N-substituted maleimides in the presence of trialkylphosphine in refluxing dioxane to afford the title compounds in good yields, which are better than those in a similar reaction using triethylphosphite reported by Haddadin et al. Many products were isolated by direct filtration from the reaction mixture... Show More