Modern Chemistry

Volume 11, Issue 1, March 2023

  • Theoretical Investigation and Synthesis Strategy of ‘hypervalent’ Carbon

    Nizam Havare

    Issue: Volume 11, Issue 1, March 2023
    Pages: 1-22
    Received: 16 December 2022
    Accepted: 9 January 2023
    Published: 30 January 2023
    Abstract: Hypervalent compounds using main group elements are often used as reagents in the variety of interesting reactions in chemistry, such as in the total synthesis of some important natural products and/or drugs, as molecular switch, as oxidizing agents, in the synthesis of novel polymers, in rearrangement reactions, in oxidative cleavage reactions, in... Show More
  • Molecular Docking of the Inhibitory Activities of Selected Phytochemicals in Artemisia Afra Against NADH-Ubiquinone Oxidoreductase of Plasmodium Falciparum (PfNDH2)

    Omolara Olubunmi Adeboye, Sunday Olawale Okeniyi, Saheed Alabi Agboluaje, Francis Oretayo Oyeleke, Olawale Folorunso Akinyele

    Issue: Volume 11, Issue 1, March 2023
    Pages: 23-33
    Received: 4 December 2022
    Accepted: 29 December 2022
    Published: 6 February 2023
    Abstract: Nicotinamide Adenine Dinucleotide Hydrogen (NADH)-ubiquinone oxidoreductase in Plasmodium falciparum (PfNDH2) constitute a feasible target for anti-malarial drug discovery. This work aims at investigating the inhibitory activities of selected phytochemicals in Artemisia Afra against NADH-Ubiquinone Oxidoreductase of Plasmodium Falciparum. 50 phytoc... Show More
  • Determination of the Antibacterial and Antioxidant Activity of Crude Extract of Bruceaantidysenterica Leaves

    Liyew Yizengaw Yitayih, Thevabakthi Siluvai Muthu Arul Jeevan, Solomon Libsu Bikilla, Tesfahun Dagnaw Demelash

    Issue: Volume 11, Issue 1, March 2023
    Pages: 34-42
    Received: 1 February 2023
    Accepted: 14 March 2023
    Published: 31 March 2023
    Abstract: Bruceaantidysenterica (abalo in Amharic) is a medicinal plant widely used in traditional medicine for treatment of several diseases and ailments. This study aimed to investigate the classes of the phytochemical constituents of the leaves of Bruceaantidysenterica extracted with the solvents of petroleum ether, ethyl acetate, and methanol. The crud e... Show More